Managing Human Immunodeficiency Virus (HIV) information resources.
Cygnus provided support to the Division of Acquired Immunodeficiency Syndrome (DAIS), National Institute of Allergy and Infectious Diseases (NIAID) in their efforts to treat HIV and opportunistic infections (OIs) that are found in association with Acquired Immunodeficiency Syndrome (AIDS). The work included abstracting, evaluation, and assembly of preclinical and supportive biological/chemical data; design, development, and maintenance of biological and chemical databases; literature searches; document identification, collection, management, and storage; software and hardware maintenance; computer update support; and web site development and maintenance. Activities included:
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Facilitating the survey, identification, retrieval, acquisition, and organization of literature on candidate drugs and agents through literature searches;
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Development and maintenance of a biomedical and chemical database;
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Expansion of the system to include literature on tuberculosis as well as processing of HIV and OI publications;
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Selected HIV and OI publications on the basis of critical expert opinion;
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Abstracting, indexing, and cataloging all articles selected for inclusion in the database;
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Biweekly transmission of selection lists to the Project Officer;
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Input chemical structures and biological data records into the HIV and OI databases from documents selected by the Project Officer and addition supplied reports;
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Providing a quick, complete overview of the current research in HIV and OIs;
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Conducting quarterly literature searches on HIV and Simian Immunodeficiency Syndrome (SIV) with selected records then abstracted and forwarded to the Project Officer;
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Advising NIAID staff on AIDS research activities;
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Development and maintenance of informational databases on AIDS-related topics using ORACLE and ISIS; and
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Designing, developing, and maintaining of public web site, including content and graphics.
