Database Systems and Information Management, DMID, NIAID, NIH

Providing computer-assisted database systems for the management of information resources on therapeutic agents for human viral infections.

Cygnus provided services to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH), for its extramural research efforts to support control and prevention of diseases caused by human infectious agents except human immunodeficiency virus.

We provided expertise in abstracting, evaluation, and assembly of preclinical and supportive biological/chemical data; database design, development, and maintenance of biological and chemical databases; scientific literature searches; document identification, collection, management, and storage; software and hardware maintenance; computer update support; and Web site design, development and maintenance. This work supported the ability to effect drug resistance research.

Cygnus provided information management and scientific support pertaining to therapeutic agents for human viral infections and included the following efforts:

  • Facilitated the survey, identification, retrieval, acquisition, and organization of literature on candidate drugs and agents through literature searches;
  • Expanded the system to include literature on TB and the processing of viral infection publications;
  • Abstracted, indexed, and cataloged all articles selected for inclusion in the database;
  • Input chemical structures and biological data records into the viral infection databases;
  • Selected viral infection publications on the basis of critical expert opinion, provide a quick and completed overview of the current research in viral infections, and advised DMID staff on viral infection research activities;
  • Developed and maintained a biomedical and chemical database; and
  • Designed, developed and maintained Web site, including content and graphics, and informational databases on viral infection-related topics including ORACLE and ISIS.

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