The following is a list of milestones from Cygnus’ origins in 1989 to present day:


The firm was incorporated in Washington, D.C., and opened for business, taking offices at 14th and I Street, N.W., Washington, D.C. and certified as a Women-Owned Small Business.

  • Cygnus was awarded its first contract:
    • 9th Special report to the U.S. Congress on Alcohol and Health, the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
  • Cygnus provided scientific and technical support for, and prepared this, 350-page report, which summarized and disseminated the current research and knowledge about alcohol abuse and alcoholism, and was one of the primary ways NIAAA updated the Nation about ongoing progress in the field of alcohol research.


    National Adoption Information Clearinghouse (NAIC), Administration for Children and Families, HHS. Cygnus operated the NAIC, a national clearinghouse that collects, develops, and disseminates a variety of information to assist the public with all aspects of adoption, especially the adoption of children with special needs. NAIC audiences include professionals, researchers, adopted children, adoptive parents, and prospective adoptive parents.

    Computer-Based Searches for Chemical Structures, NCI, NIH, HHS. In support of the efforts of NCI to find new and better treatments for various illnesses, the following services were provided:

    • Conducted full-structure and substructure chemical database searches.
    • Performed data-item searches (approximately 1,750 per year) of the Developmental Therapeutics Program databases.
    • Conducted bibliographic database searches (MEDLARS/MEDLINE, CANCERLIT, CANCERLINE, TOXLINE, CAS ONLINE, AIDSLINE, BIOSIS, AGRICOLA, etc.).
    • Generated systematic CAS nomenclature and citation of source authorities.
    • Maintained log of searches performed that encompassed the history, components, and results of each search.
    • Maintained information on the SAVE, STRUCTURES, QUERY, and RESULTS files and the current state of each section.
    • Monitored and pinpointed system search shortcomings, problems, and deficiencies.
    • Adjusted search formulations or strategies.
    • Maintained awareness of the design, structure, content, and operating characteristics of the NCI Drug Information System.
    • Generated chemical names for approximately 600 compounds per year.
    • Maintained special files to facilitate the processing of searches, including format statements, query structures, search outputs, utility programs, correspondence files, and chemical names. All files were archived to magnetic tape for quality control and security.

    Study of the Impact on Service Delivery of Families with Substance Abuse Problems, Administration for Children and Families, HHS. This research effort assessed how changes in the incidence of substance abuse impacted human service programs administered by the Administration for Children, Youth and Families, such as foster care, child protective services, runaway and homeless youth services, Head Start, Head Start parent-child centers, and Comprehensive Child Development Program projects. The primary purpose of the study was to assess both the size and nature of the impact of substance abuse on these various service delivery systems.

    Drug-Free Workplace Helpline, Center for Substance Abuse Prevention, Substance Abuse and Mental Health Services Administration, HHS. The toll-free Drug-Free Workplace Helpline provides information and confidential technical assistance to business, industry, unions, and community organizations on developing and implementing comprehensive drug-free workplace programs. Cygnus operated the Helpline, which averaged 1,000 calls per month, and oversaw the storage and dissemination of information materials as well as data collection and analysis. The Helpline provided individualized telephone consultation, which included resource referrals, networking services, and publications to assist in planning, policy development, and program implementation. Calls received were primarily from managers, directors, and owners of companies with 500 or fewer employees. Helpline information specialists were trained to give specific information tailored to each organization’s unique characteristics. Depending on the needs of the caller, the Helpline staff provided information on the following topics:

    • Assessing the nature and extent of drug abuse in an organization;
    • Developing and implementing a drug abuse policy;
    • Choosing an employee assistance program model compatible with individual organizations, including organizational benefits programs;
    • Implementing employee education and supervisor training;
    • Evaluating the effectiveness of a drug abuse program in terms of cost and human factors;
    • Understanding the technical, legal, and employee relations aspects of drug testing; and
    • Identifying signs and symptoms of drug abuse.

    Technical Support Services: Division of Basic Sciences, NCI, NIH, HHS. Cygnus provided a wide range of services to NCI’s Division of Basic Sciences, including publication development, scientific manuscript editing, graphic design and production, database development, onsite computer support, conference support, and property management.

    Grant Application Review Support Services, Bureau of Justice Assistance (BJA), Office of Justice Programs, U.S. Department of Justice. BJA, an arm of the Office of Justice Programs, submitted competitive grant programs applications it received to be peer reviewed by outside experts comprising both criminal justice researchers and practitioners. Delivery of this technical assistance to BJA by expert peer reviewers was coordinated through an outside contractor. Cygnus served as BJA’s peer review technical assistance contractor.

    Development of Training and Education Materials on Drugs in the Workplace, Center for Substance Abuse Prevention, Substance Abuse and Mental Health Services Administration, HHS. Cygnus created a kit of materials to assist the business community, particularly small- and medium-sized businesses, with developing and implementing drug-free workplace programs. The kit, entitled Making Your Workplace Drug Free: A Kit for Employers, won first place for publications in the 13th Annual Markie Awards. Markies are awarded for excellence in alcoholism and addiction communications and marketing. The kit imparted research findings about the effects of alcohol and drug abuse as well as information on preventing and managing alcohol, tobacco, and other drug abuse in the workplace. The materials addressed many issues, including educating employees about substance abuse, helping family and friends who suffer an addiction, and providing advice for parents concerned about their children. Cygnus was selected to develop the kit as part of an intense project that involved market research, translation of the research on drug-free workplaces and substance abuse for use by employers, publications development and production, development of a dissemination plan, and field tests. The project was completed under particularly narrow time constraints. More than 40,000 copies of the kit have been distributed to date.

    Technical Support Services, National Institute on Alcohol Abuse and Alcoholism, HHS. Cygnus provided a variety of services to the Office of the Director of this Institute, including:

    • Scientific writing, editing, proofreading, and publication management;
    • Information retrieval, synthesis, and analysis;
    • Publication production;
    • Graphics and desktop publishing;
    • Technical assistance with management information systems;
    • Administrative support for grants management; and
    • Conference support.

    Publications Services for the Secretary’s Conference to Develop a National Action Plan on Breast Cancer, Secretary of Health and Human Services, HHS. Cygnus helped HHS prepare for a high-level, politically sensitive, high-visibility conference convened by the Secretary of HHS to initiate the development of a national action plan on breast cancer. The conference brought together medical researchers, legislators, breast cancer advocacy groups, and representatives from every Federal agency connected with breast cancer research, treatment, education, and prevention. The media were well represented, and the conference received national attention. NIH spearheaded the planning activities. Cygnus organized all aspects of the conference within a 60-day window, and provided meeting and scientific writing support. Cygnus was responsible for collecting a vast assortment of materials on breast cancer, ranging from bumper stickers to published research manuscripts. We meticulously cataloged more than 250 different documents and prepared a bibliography that each participant received onsite. Preparation of the bibliography required careful proofreading to ensure that all references were completely and correctly cited. A resource room was set up at the conference that contained copies of all materials included in the bibliography.

    Support Services for the 1998 and 2000 Surgeon General Reports on Smoking and Health: Tobacco Use Among U.S. Racial/Ethnic Minority Groups, and Reducing Tobacco Use, Office on Smoking and Health, CDC, HHS. Cygnus produced two Surgeon General’s reports on smoking: Tobacco Use Among U.S. Racial/Ethnic Minority Groups and Reducing Tobacco Use. These reports updated the Nation on the growing scientific knowledge base about the health consequences of smoking and served as a basis for public and private efforts to improve the health of millions of Americans through smoking-cessation campaigns and related activities. The Surgeon General’s reports are one of the most visible initiatives of the Office on Smoking and Health. The information is presented to a broad audience consisting of Congress, the public, and researchers to stimulate scientific, investigative, and practitioner progress as well as promoting changes in national policy toward discouraging tobacco use. This complex project entailed the provision of a full range of scientific and technical editorial support.

    Alzheimer’s Disease Education and Referral (ADEAR) Center, National Institute on Aging, NIH, HHS. The primary goal of the ADEAR Center was to provide information on Alzheimer's disease, its consequences and potential treatments, new research, and available services to physicians and other health professionals, patients, and their families, and the public through a 1-800 toll-free telephone service.

    Editorial Support Services, National Center for Chronic Disease Prevention and Health Promotion, CDC, HHS. Cygnus served as the editorial services branch of CDC’s National Center for Chronic Disease Prevention and Health Promotion, providing continuous, consistent, and high-quality review of publications and other communication materials for educational, technical, behavioral, scientific, and health sciences uses. Topic areas covered included tobacco use, maternal and infant health, education and community-based programs, family planning, physical activity and fitness, heart disease and stroke, nutrition, the needs of special populations, cancer, diabetes and chronic disabling conditions, HIV infection, surveillance and data systems, and age-related illnesses. The contract required the complete spectrum of materials development services, from the conceptualization and writing of health education and scientific materials through production. Cygnus also provided peripheral services, such as readability testing, translation and transcription services, and dissemination efforts, including distribution via the Internet.

    Information Clearinghouse and Related Support Services, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, HHS. The National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse (NAMSIC) was the central Federal source of information on professional, patient, and public education materials and programs related to rheumatic, musculoskeletal, and skin diseases. The Clearinghouse relied on biomedical, health communication, and epidemiologic research to determine the appropriate audiences, information needs of its audiences, and channels through which audiences can best be reached. Cygnus supported NAMSIC by carrying out the following tasks:

    Developing an annual program plan for all Clearinghouse activities;

    Answering more than 2,000 written and telephone requests from lay and professional audiences each month, including providing information on treatments; causes, prevention, detection, diagnosis, rehabilitation, and epidemiology; psychosocial aspects; voluntary and professional organizations related to the diseases; and other sources of materials and information;

    Storing, distributing, and maintaining an inventory of 200,000 publications related to diseases;

    Using a single automated system to record and track requester information from time of initial request to fulfillment of orders, including tracking the publications inventory;

    Conducting research to determine the information needs of requesters, the most effective use of existing resources, and the cost-effectiveness of various approaches to disseminating information;

    Developing scientific, technical, health education, and promotional materials, which included researching, writing, market researching, field testing, and providing full editorial and production support for scientific manuscripts, factsheets, bibliographies, brochures, and information packages that addressed specific diseases as well as developing audiovisual materials such as slide shows and audiotapes;

    Maintaining a database with full bibliographic citation and abstracts that was a subfile of the Combined Health Information Database, a commercially available Federal health database that focuses on information not readily available elsewhere;

    Developing an on-demand system to allow persons making inquiries to retrieve health information from the Clearinghouse almost instantly; and

    Supporting health education campaigns, particularly in areas related to prevention of disease and disability. Support included developing comprehensive plans for new and existing campaigns; performing literature searches to identify existing information/programs/materials; constructing profiles of the target audiences; identifying intermediary organizations with which Cygnus could collaborate to develop new programs or reach new audiences; writing, producing, and disseminating materials; and pretesting and evaluating materials.

    Support Services for the National Advisory Boards, Committees of the Advisory Boards, Interagency Coordinating Committees, and Other NIDDK Committees, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, HHS. Cygnus supported the NIDDK’s National Advisory Boards, Interagency Coordinating Committees, and other NIDDK Committees, including the End Stage Renal Disease Data Advisory Committee. Cygnus staff supported the Boards and Committees by providing technical support in the areas of national public health policy assessment and program planning and evaluation, publications and documentation support, graphics services, conference management and logistical support, support for special initiatives, and administrative and quick response services.

    Social Environments and Psychological Function in Older People: A Longitudinal Follow-up, National Institute of Mental Health (NIMH), NIH, HHS. Cygnus collected in-person interview data and extensive background information on a national sample of older individuals who had been part of a longitudinal study of aging that began in 1964. A portion of the original sample was interviewed again in 1974. This study followed the same sample population, creating particular difficulties in finding the individuals, many of whom had moved or were critically ill or had passed away. This, in turn, created special statistical sampling and interviewing challenges, which Cygnus was able to meet successfully. The data have been and will continue to be analyzed by NIMH to examine how such factors as environmental complexity, social support, financial resources, and physical health affect and are affected by cognitive functioning, autonomous self-directed orientations and values, coping behavior, and feelings about oneself and one’s circumstances. The conclusions drawn from this study were of great value in the development of environments and the planning of services for older persons that will increase the likelihood that their later years will be fulfilling and satisfying.


    Tobacco Information Dissemination Program, Office on Smoking and Health, CDC, HHS. Cygnus managed two major components of the CDC’s Tobacco Information Dissemination Program:

    Information management: Cygnus developed several systems to greatly enhance the public’s access to information on the health consequences of smoking. Cygnus staff members designed and built a comprehensive bibliographic database of tobacco and health citations that was available online. The database included the most recent research findings, prevention and education tools, and information of historical importance, such as legislation and health policy research. Cygnus created a taxonomy of smoking and health to be used to categorize all smoking and health information within CDC. With that information, Cygnus developed a thesaurus and then indexed the entries in the database, which facilitated searching. It is anticipated that this thesaurus would be published and made available as a tool for researchers and laypersons alike. Throughout the development and maintenance of this database, Cygnus continued to provide current education and awareness services by searching online databases, such as DIALOG, OVID, and CHID. In addition to monitoring published information on tobacco and health, Cygnus created priority topic reviews on certain smoking issues based on recent research findings and developed factsheets for distribution to the public.

    Operation of the media campaign resource center for tobacco control: Through this center, Cygnus responded to requests for tobacco control advertising materials for TV, radio, print, and out-of-home. Cygnus assisted tobacco control coordinators in each State in developing media campaigns using the available materials and coordinated the tagging, duplication, and shipping of broadcast-quality TV and radio spots and camera-ready print and out-of-home advertisements. Cygnus entered all of the orders into a database that generated monthly reports and graphs showing total requests by month for each medium. Cygnus coordinated special mailings of flyers and direct mail pieces to each tobacco control coordinator, keeping them apprised of new materials and advertising opportunities. Cygnus also developed an evaluation survey to collect feedback about the Resource Center.

    National Center for Complementary and Alternative Medicine (NCCAM) Clearinghouse, National Center for Complementary and Alternative Medicine, NIH, HHS. Cygnus assumed the management of the NCCAM Clearinghouse. This NCCAM project was formerly the Office of Alternative Medicine (OAM) Clearinghouse/Publication and Research Database. The following were major Clearinghouse activities:

    • Health information management, processing, and retrieval. Developed and implemented systems and procedures for processing over 2,000 toll-free telephone, written, fax, and e-mail requests per month for information about complementary and alternative medicine. Ensured that the information management system is capable of handling current and expected growth in information requests averaging roughly 200 percent.
    • Health information response and referral. Provided consistent and appropriate responses to inquiries from health professionals, patients and their families, and the public on the state of scientific research sponsored by NCCAM and making referrals to NCCAM-approved information sources.
    • Health education materials and publications design, development, and production. Developed, wrote, and produced health and biomedical materials and publications to inform and guide health professionals, policymakers, and the public. Developed layout, format, and a unique logo for Clearinghouse publications. Wrote, edited, and produced the NCCAM quarterly newsletter in accordance with NCCAM’s requirements. Provided scientific writing, substantive editing, copyediting, and proofreading.
    • Health education, communication, outreach, and promotion. Disseminated health publications and educational materials to inform and guide health professionals, policymakers, and the public. Tracked, compiled, and distributed popular press articles on complementary and alternative medicine issues and NCCAM. Provided content materials in HTML format for the NCCAM Website, including the newsletter and popular publications. Developed and maintained an on-demand system enabling NCCAM constituents instant access to paper copies of the Clearinghouse’s most useful and popular publications. Supported the NCCAM Public Information Officer in media relations activities as directed by the NCCAM Project Officer.
    • Database design, implementation, and development. Designed, developed, and maintained the NCCAM subfield of the Combined Health Information Database (CHID), a commercially available Federal database that focuses on health information for the public. The NCCAM subfile of CHID provides complementary medicine information abstracted from books, factsheets, journal and magazine articles, brochures, scientific research papers, and information packages on various complementary medicine modalities. Developed a Response and Referral Database containing comprehensive information on alternative and complementary medicine modalities, a listing of alternative medicine associations and organizations, and the entire Clearinghouse’s publications.
    • Warehousing and distribution. Stored, distributed, and maintained an inventory of documents relating to NCCAM’s scientific research initiatives. Stored inventory of and distributed health publications and educational materials on complementary medicine to inform and guide health professionals, policymakers, and the public.

    · Management of Information Resources on Therapeutic Agents for HIV and Opportunistic Infections, Division of Acquired Immunodeficiency Syndrome, National Institute of Allergy and Infectious Diseases (NIAID), NIH, HHS. Cygnus provided support to NIAID in its efforts to better understand how to treat HIV and the opportunistic infections (OIs) that are found in association with AIDS. Cygnus’ efforts included the following tasks:

    • Facilitated the survey, identification, retrieval, acquisition, and organization of literature on candidate drugs and agents through literature searches.
    • Developed and maintained a biomedical and chemical database.
    • Expanded the system to include literature on tuberculosis as well as processing of HIV and OI publications.
    • Selected HIV and OI publications on the basis of critical expert opinion.
    • Abstracted, indexed, and cataloged all articles selected for inclusion in the database.
    • Biweekly transmission of selection lists to the Project Officer.
    • Input chemical structures and biological data records into the HIV and OI databases from documents selected by the Project Officer and from reports supplied by other contractors.
    • Provided a quick, complete overview of the current research in HIV and OIs.
    • Conducted quarterly literature searches on HIV and SIV. Selected records were abstracted and forwarded to the Project Officer.
    • Advised NIAID staff on AIDS research activities.
    • Developed and maintained informational databases on AIDS-related topics using ORACLE and ISIS.
    • Designed and developed Web page content and graphics.

    Support Services for the 2004 and 2006 Surgeon General’s Reports on Smoking and Health:·Health Consequences of Smoking, and Health Consequences of Involuntary Exposure to Tobacco Smoke, Office on Smoking and Health, CDC, HHS. Cygnus was awarded a 3-year contract to produce two Surgeon General’s reports (SGRs) on smoking health: Health Consequences of Tobacco Use and Health Consequences of Involuntary Exposure to Tobacco Smoke. These reports updated the Nation on the growing base of scientific knowledge about the health consequences of active smoking and the effects of involuntary smoking on the health of individuals who are not active smokers. The reports serve as a basis for public and private efforts to improve the health of millions of Americans through smoking-cessation campaigns and related activities. The SGRs are the most visible initiatives of the Office on Smoking and Health. The scientifically based information is presented to a broad audience consisting of Congress, the public, and researchers to stimulate scientific, investigative, and practitioner progress. It also is the basis for making changes in national policy related to tobacco use in this country and elsewhere. This complex project required Cygnus to provide the full range of scientific and technical editorial support services.


    • Cygnus moves to new offices to accommodate its growing staff. Cygnus grows to a staff of more than 75 professionals, including those with some of the following specializations: social and behavioral research, epidemiology, IT services, chemical and health database expertise, biomedical indexing, health policy, health communications and publications, human capital and organizational development specialist, and event planning.
    • General Research and Support Services Agency for Healthcare Research and Quality (AHRQ), HHS. Cygnus provided a broad range of management and research services to support AHRQ activities. AHRQ issued approximately 347 Work Assignments during the initial contract. Descriptions of some of the AHRQ assignments included planning, scheduling, arranging, managing, and reporting on approximately 60 meetings annually. Meetings ranged in length from 1–3 days with 10 to 300 participants; Prepared specific substantive health services research and health policy materials and documents. This included conducting focus groups and other activities required to address research and policy questions and issues and to develop options and methods by which to attain AHRQ research and policy goals; prepared materials and documents required to support AHRQ meetings (e.g., briefing books/packets); prepared scientific summaries and research reports to support AHRQ meetings proceedings and executive summaries for various AHRQ audiences; and provided administrative support as requested to support AHRQ operations (e.g., supporting Extranets for various AHRQ programs).
    • Support Services for the 2010 Surgeon General’s Report on Smoking and Health, How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Tobacco-Attributable Disease, Office on Smoking and Health, CDC, HHS. Under this contract, Cygnus supported the production of a Surgeon General’s report (SGR) on smoking and health. The SGRs are one of the most visible initiatives of the Office on Smoking and Health. The information is presented to a broad audience—consisting of Congress, the public, and researchers—to stimulate scientific, investigative, and practitioner progress as well as the making of changes in national policy toward discouraging the use of tobacco.
    • Substance Registration System Database Standardization and Update, U.S. Food and Drug Administration (FDA), HHS. Cygnus staff is responsible for updating the FDA’s chemical structures for use in the Substance Registration System (SRS). The SRS assigns unique identification codes, UNII codes, to individual substances. Cygnus staff verifies that the chemical structures are correct by comparing the structures to their representations and to their names in FDA’s printed ingredient dictionary, the USAN dictionary, the USP, and other authoritative sources. Particular emphasis is placed on adding and correcting stereochemistry to ensure that a substance has a single unique entry in the database.

    The SRS is an ambitious project where the FDA is trying to standardize and codify all ingredients and components that go into approved medicinal products. The unique identifiers that it generates will be available to the general public so medicinal materials can be unambiguously identified. Presently, Cygnus staff is reviewing 24,000 substances, of which 12,000 can be represented with a structure(s).


    • OWER Learning and Development Support Services, Office of Workforce Effectiveness and Resources (OWER), NIAID, NIH, HHS. Cygnus provided strategic, programmatic, and operational support to OWER in the areas of learning and organizational development. Cygnus has provided more than 200 offerings to support NIAID’s missions and goals. This support includes design and development of formal course presentations, one-on-one coaching services, organizational consulting services and interventions, program evaluation, focus group and needs assessment services, meeting logistics and facilitation, and publication and writing support. Descriptions of some of the OWER programs and assignments that encompass the variety of services required are described briefly below. Program offerings include:
      • Navigating NIAID Welcome Workshop (NNWW) and New Employee On-Boarding Program—A year-long program to assist with the assimilation and integration of new staff to NIAID beginning with a mandatory orientation.
      • The Art of Leadership (AOL)—A multisession program open to GS-12s and above to develop and enhance their leadership skills. It includes a leadership coaching component of one-on-one guidance from a qualified leadership coach.
      • The Essentials of Supervision (EOS)—A mandatory program of seven sessions for supervisors with 5 or less years of supervisory experience with NIAID to provide knowledge and tools for supervision at NIAID. It includes a 360° feedback tool and two individual coaching sessions on the feedback.
      • Executive Coaching (EC) Program—Available one-on-one guidance from a certified executive coach (ICF Certified) to assist senior leaders with meeting short- and long-term goals.
      • In addition to direct facilitation, provide coaching services to NIAID leaders via Art of Leadership, the Essentials of Supervision, and Executive Coaching.
      • Unit-based Training and Services (UBT)—Professional assistance is available to management and their teams, and includes such topics as organizational diagnosis, project management, time management, team building, conflict management, and customized training.
      • Career Development (CD)—Classes in specialized topics to assist NIAID staff in fully developing their careers and career potential. Held Career Development classes for 132 employees including video casts and in-person classes at Rocky Mountain Labs. Topics included Email Excellence, Making Your Best Speech Ever, Powerful Presentations, Scientific Presentations and Individual Development Plans and Effective Communication and Customer Service.
      • Organizational Consulting Services (OCS)—Provides organizational development consulting, interventions, customized training, conflict management, team building, retreat design, and facilitation.


    • Logistical Management Support for Evidence-based Practice Centers (EPCs) Meeting(s), Evidence-based Practice Center and Johns Hopkins University (JHU). Cygnus provided planning, management, logistics, clerical, and scientific and other materials development support to the JHU EPC. JHU served as the host center for the annual Spring 2010 EPC Meeting. The meeting was sponsored by the Agency for Healthcare Research and Quality for convening its EPC grantee organizations.
    • Breast Cancer and the Environmental Research Program (BCERP), Needs Assessment National Institute of Environmental Health Sciences and NCI, NIH, HHS. The primary objective of this project was to conduct a needs assessment for BCERP research translation and dissemination. The assessment project will determine whether existing information materials, developed by the four BCERP-funded Breast Cancer and the Environment Research Centers and their partner, Community Outreach and Translation Core during the period of 2003 to 2010, are sufficient as is, should be modified, or whether entirely new materials are needed for each target audience, and what formats will be most effective for informational materials.
    • Pandemic Influenza Digital Archive (PIDA) Pilot Project, Division of Library Services (DLS), NIH, HHS. NIH’s DLS supports the information needs of NIH scientific, clinical, and administrative staff. The DLS has partnered with NIAID to create a pandemic influenza digital archive. A large collection of core documents concerning the 1918 influenza pandemic have been identified and collected by Dr. David Morens, a virologist with NIAID. This collection is comprised primarily of journal articles, but also includes statistical data, e-mails, correspondence, books and book chapters, bibliographies, and abstracts. NIAID wishes to use this collection as the starting point and initial collection for a PIDA database. The NIH Library has been asked to create a Web-based bibliography of these materials complete with full metadata, PDFs or links to the full-text, and OCR PDFs that can be text mined. Cygnus established indexing standards for pandemic influenza publications and created a test file of indexed documents. Indexing standards and procedures were established for metadata fields and documents were then analyzed and indexed.
    • Prepare Four Annual NIST Center for Neutron Research (NCNR), Accomplishments and Opportunities Reports, National Institute of Standards and Technology (NIST), U.S. Department of Commerce. On an annual basis since 2007, Cygnus prepared four, 80–100 page, annual Accomplishments and Opportunities Reports for the NCNR. Cygnus was responsible for developing the cover, design concept, and interior layout; incorporating text; selecting full-color and photographs; resizing and optimizing artwork, tables, and figures; editing, reference verification, proofreading, and print production. The first two reports produced under this contract were the 2010 Accomplishments and Opportunities Report and the 2010 Accomplishments and Opportunities Report.
    • BCRS Organizational Framework, Bureau of Clinician Recruitment Service (BCRS), Health Resources and Services Administration (HRSA), HHS. The BCRS addresses the nationwide shortage of healthcare providers through scholarship and loan repayment programs that help underserved communities and shortage facilities recruit and retain qualified health professionals. With the expansion of BCRS programs, funding, and responsibilities, an increase in hiring shortly followed. This increase in staff levels added to the new Bureau and program responsibilities and created a need to focus on Organizational Development and Design. The goal of the BCRS Organizational Development and Design effort is to improve the clarity of BCRS’ positions and duties and to integrate HRSA competencies into its most prominent job skills. Clearer position descriptions, aligned competencies, and better supervision through a 360° Management Assessment process will result in greater, more effective organizational capacity; a higher performance work culture; and better employee satisfaction.
    • ChemIDplus Database Administration and Maintenance and FDA/NLM Interagency Support Services, NLM, NIH, HHS. Cygnus staff is responsible for adding and maintaining chemical structures and biomedical data for NLM’s ChemIDplus and Drug Information Portal databases ( ChemIDplus is a Web-based search system that provides access to structure and nomenclature authority files used for the identification of chemical substances cited in NLM databases, including the TOXNET® system. ChemIDplus also provides structure searching and direct links to many biomedical resources at NLM and on the Internet for chemicals of interest. The database contains more than 380,000 chemical records, of which more than 289,000 include chemical structures, and is searchable by Name, Synonym, CAS Registry Number, Molecular Formula, Classification Code, Locator Code, Structure, Toxicity, and/or Physical properties. The ChemIDplus database is linked to PubMed and a variety of other Web resources that provide biomedical information. ChemIDplus is used by chemists and biological scientists through the world to search for information on compounds that may have biochemical, pharmaceutical, medicinal, and biological importance.
    • Facilitation Services for the Office of Research on Women’s Health (ORWH), Office of the Director, NIH, HHS. Cygnus provided facilitation and training to ORWH staff covering topics on appreciation of personal differences and how they benefit the organization, conflict resolution, change management, and stress management for a group of 15–20 staff.
    • Leadership Development Program for the Office of Research on Women’s Health (ORWH), NIH, HHS. Cygnus used a framework that utilizes methods from both Results Based Leadership and the Action Learning Team (ALT) approaches to enhance leadership development. The work with the teams was organized around specific results and development of skills within each of the identified leadership competencies. ORWH staff groups are focusing on the following leadership and communicative abilities and competencies:
      • Building Communication Competencies
      • Building Results-based ALT Competencies
      • Office-wide Introduction and Coaching
      • Team Coaching
    • Indexing Journal Articles in Biomedical Literature, NLM, NIH, HHS. The Cygnus biomedical indexing team prepares biomedical and scientific bibliographic citations for entry into national and international databases. This includes our long-running work for MEDLINE®, NLM’s premier bibliographic database that is the primary component of PubMed®. PubMed comprises more than 20 million citations for biomedical literature from MEDLINE® life sciences journals, and online books, with and 3,000-5,000 references added daily.

    Cygnus provides high-quality indexing services to NLM and assisted in the review, correction, and enhancement of bibliographic citation data for MEDLINE®. Cygnus presently provides MeSH indexing for some 124,000 biomedical journal articles annually in English, Spanish, and 12 other foreign languages, with a 99.8% acceptance rate. Led by our Senior Medical Librarian, our staff of indexing professionals are experienced in researching, identifying, reviewing, and indexing scientific literature for MEDLINE. In addition, Cygnus has worked closely with NLM on the Medical Text Indexer Frontline (MTIFL) Pilot Study to determine the feasibility of substantial automation of the indexing process. Our role in this process ensures that researchers around the world can find, review, and incorporate today’s most up-to-date scientific knowledge into their research projects. Each member of our indexing team has advanced scientific degrees and substantial indexing and scientific pedigrees. Most hold Ph.D.’s and/or M.D.’s in relevant

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